p68 c-rel

《英文msh词典》p68 c-rel
[入口词] p68 c-rel
[主题词] Proto-Oncogene Proteins c-rel
[英文释义] Cellular DNA-binding proteins encoded by the rel gene (GENES,REL). They are expressed predominately in hematopoietic cells and may play a role in lymphocyte differentiation. Rel frequently combines with other related proteins (NF-KAPPA B,I-kappa B,relA) to form heterodimers that regulate transcription. Rearrangement or overexpression of c-rel can cause tumorigenesis.